The genetic factor influencing pulmonary hypertension in cattle at high altitude

E. K. Weir; A. Tucker; J. T. Reeves; D. H. Will; R. F. Grover

The genetic factor influencing pulmonary hypertension in cattle at high altitude

E. K. Weir, A. Tucker, J. T. Reeves, D. H. Will, R. F. Grover

Medicine - Veteran's Administration Medical Center

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

Susceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F ₂α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.

Original language	English (US)
Pages (from-to)	745-749
Number of pages	5
Journal	Cardiovascular Research
Volume	8
Issue number	6
State	Published - Dec 1 1974

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title = "The genetic factor influencing pulmonary hypertension in cattle at high altitude",

abstract = "Susceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F 2α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.",

author = "Weir, {E. K.} and A. Tucker and Reeves, {J. T.} and Will, {D. H.} and Grover, {R. F.}",

year = "1974",

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language = "English (US)",

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AU - Weir, E. K.

AU - Tucker, A.

AU - Reeves, J. T.

AU - Will, D. H.

AU - Grover, R. F.

PY - 1974/12/1

Y1 - 1974/12/1

N2 - Susceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F 2α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.

AB - Susceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F 2α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.

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