The impact of NAT2 acetylator genotype on mutagenesis and DNA adducts from 2-amino-9H-pyrido[2,3-b]indole

Chemical Compounds

• 2-Amino-9H-pyrido[2,3-b]indole 86%
• Genetic Polymorphism 77%
• Smoke 55%
• Indole 45%
• Mutation 41%
• Adduct 34%
• Hypoxanthine 30%
• Genotoxicity 29%
• Genotoxic 28%
• Carcinogenic 25%
• Aromatic Amine 25%
• Cytochrome 21%
• Nucleotide 19%
• Metabolite 17%
• Amine 15%
• Ester 14%

Medicine & Life Sciences

• 2-amino-9H-pyrido(2,3-b)indole 100%
• DNA Adducts 60%
• Mutagenesis 47%
• Genotype 34%
• Deoxyguanosine 28%
• Meat 21%
• Cricetulus 20%
• Amines 20%
• Genetic Polymorphisms 20%
• Smoke 18%
• Ovary 17%
• indole 12%
• Hypoxanthine 12%
• Mutation 10%
• Tobacco Use 10%
• Transferases 9%
• Esters 9%
• Cytochrome P-450 Enzyme System 9%
• Tobacco 9%
• DNA Repair 9%
• Epidemiologic Studies 8%
• Alleles 7%
• Phenotype 5%
• Cell Line 5%
• DNA 5%
• Enzymes 5%
• Neoplasms 3%