The influence of vasopressin on upper gastrointestinal blood flow

John P. Delaney, Robert L. Goodale, John Cheng, Owen H. Wangensteen

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Tissue blood How was compared by means of the radioisotope distribution technique in anesthetized dogs receiving intravenous Pitressin and in a comparable control group. The drug effected reductions in How to the esophagus (-65 percent), stomach -67 percent). duodenum (-43 percent), and pancres (-83 percent). Blood flow in the mucosa of the gastric body was reduced by 75 percent. Pitressin should prove to be a useful adjunct in the management of many patients with tipper gastrointestinal bleeding.

Original languageEnglish (US)
Pages (from-to)397-400
Number of pages4
JournalSurgery
Volume59
Issue number3
StatePublished - Mar 1 1966

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