In this study, we proposed and tested an interaction between positive affectivity (PA) and job satisfaction in predicting two organizationally relevant job attitudes, frustration and intention to quit. Specifically, we predicted that job satisfaction would be strongly and negatively related to frustration and intention to quit among high-PA, but not low-PA, individuals. The predictions were tested using survey data from commercial bank employees (N = 172) in the United Arab Emirates. Hierarchical regressions supported the hypothesized interactions for both dependent variables. The results contribute to the evidence that high-PA can be associated with generally unfavorable organizational outcomes in certain situations, and they point to the stability of dispositional research in different cultures.