The organization and rate of evolution of wheat genomes are correlated with recombination rates along chromosomes arms

Eduard D. Akhunov, Andrew W. Goodyear, Shu Geng, Li Li Qi, Benjamin Echalier, Bikram S. Gill, A. Miftahudin, J. Perry Gustafson, Gerard Lazo, Shiaoman Chao, Olin D. Anderson, Anna M. Linkiewicz, Jorge Dubcovsky, Mauricio La Rota, Mark E. Sorrells, Deshui Zhang, Henry T. Nguyen, Venugopal Kalavacharla, Khwaja Hossain, Shahryar F. KianianJunhua Peng, Nora L.V. Lapitan, Jose L. Gonzalez-Hernandez, James A. Anderson, Dong Woog Choi, Timothy J. Close, Muharrem Dilbirligi, Kulvinder S. Gill, M. Kay Walker-Simmons, Camille Steber, Patrick E. McGuire, Calvin O. Qualset, Jan Dvorak

Research output: Contribution to journalArticlepeer-review

249 Scopus citations

Abstract

Genes detected by wheat expressed sequence tags (ESTs) were mapped into chromosome bins delineated by breakpoints of 159 overlapping deletions. These data were used to assess the organizational and evolutionary aspects of wheat genomes. Relative gene density and recombination rate increased with the relative distance of a bin from the centromere. Single-gene loci present once in the wheat genomes were found predominantly in the proximal, low-recombination regions, while multigene loci tended to be more frequent in distal, high-recombination regions. One-quarter of all gene motifs within wheat genomes were represented by two or more duplicated loci (paralogous sets). For 40 such sets, ancestral loci and loci derived from them by duplication were identified. Loci derived by duplication were most frequently located in distal, high-recom bi nation chromosome regions whereas ancestral loci were most frequently located proximal to them. It is suggested that recombination has played a central role in the evolution of wheat genome structure and that gradients of recombination rates along chromosome arms promote more rapid rates of genome evolution in distal, high-recombination regions than in proximal, low-recombination regions.

Original languageEnglish (US)
Pages (from-to)753-763
Number of pages11
JournalGenome research
Volume13
Issue number5
DOIs
StatePublished - May 1 2003

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