Postarthroplasty infection is a devastating complication. In some patients, virulent pathogens or poor health complicate reconstruction. Resection arthroplasty is a viable option in such cases. Seven patients with resection arthroplasty following infection after shoulder arthroplasty were reviewed retrospectively at an average 20- month follow-up (range, 12-41). Average time between the initial procedure and the first debridement was 59.5 months (4-151 months). The average number of debridements was 2.2 per patient (range, 1-4 procedures). There were no complications, no recurrence of deep infection, no nerve damage, and no fractures. All patients were able to reach the opposite axilla, their backpocket and perineum, and their mouth. All but 1 patient were satisfied with their result. No patient had a satisfactory outcome via Neer's criteria. Resection arthroplasty is a reasonable salvage option for patients who are not good candidates for prosthetic reimplantation. This yields patients who can reliably perform basic activities of daily living.