The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin

Alvin J. Beitz; R. David Shepard; William E. Wells

doi:10.1016/0006-8993(83)91292-1

The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin

Alvin J. Beitz, R. David Shepard, William E. Wells

Chronic Disease Biology

Research output: Contribution to journal › Article › peer-review

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Abstract

The retrograde transport-HRP-immunocytochemical technique was employed to ascertain if the periaqueductal gray-raphe magnus projection arises from neurons containing somatostatin, neurotensi, serotonin or cholecystokinin. Following HRP injections into the raphe magnus (NRM) double-labeled cells containing HRP reaction product and somatostatin-, neurotensin- or serotonin-like immunoreactivity were identified in the midbrain periaqueductal gray (PAG). No cholecystokinin-like immunoreactive double-labeled neurons were found in the PAG. These results indicate that the PAG-NRM pathway contains somatostatin, neurotensin and serotonin but not cholecystokinin.

Original language	English (US)
Pages (from-to)	132-137
Number of pages	6
Journal	Brain Research
Volume	261
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(83)91292-1
State	Published - Feb 14 1983

Bibliographical note

Funding Information:
This work was supported by NSF Grant BSN 7906486 and in part by USPHS Grant NS 17401.

Keywords

cholecystokinin
neurotensin
nucleus raphe magnus
serotonin
somatostatin

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title = "The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin",

abstract = "The retrograde transport-HRP-immunocytochemical technique was employed to ascertain if the periaqueductal gray-raphe magnus projection arises from neurons containing somatostatin, neurotensi, serotonin or cholecystokinin. Following HRP injections into the raphe magnus (NRM) double-labeled cells containing HRP reaction product and somatostatin-, neurotensin- or serotonin-like immunoreactivity were identified in the midbrain periaqueductal gray (PAG). No cholecystokinin-like immunoreactive double-labeled neurons were found in the PAG. These results indicate that the PAG-NRM pathway contains somatostatin, neurotensin and serotonin but not cholecystokinin.",

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AU - Shepard, R. David

AU - Wells, William E.

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The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin

Abstract

Bibliographical note

Keywords

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