The structure of cognition in 9 and 10 year-old children and associations with problem behaviors: Findings from the ABCD study's baseline neurocognitive battery

Wesley K. Thompson, Deanna M. Barch, James M. Bjork, Raul Gonzalez, Bonnie J. Nagel, Sara Jo Nixon, Monica Luciana

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The Adolescent Brain Cognitive Development (ABCD) study is poised to be the largest single-cohort long-term longitudinal study of neurodevelopment and child health in the United States. Baseline data on N= 4521 children aged 9–10 were released for public access on November 2, 2018. In this paper we performed principal component analyses of the neurocognitive assessments administered to the baseline sample. The neurocognitive battery included seven measures from the NIH Toolbox as well as five other tasks. We implemented a Bayesian Probabilistic Principal Components Analysis (BPPCA) model that incorporated nesting of subjects within families and within data collection sites. We extracted varimax-rotated component scores from a three-component model and associated these scores with parent-rated Child Behavior Checklist (CBCL) internalizing, externalizing, and stress reactivity. We found evidence for three broad components that encompass general cognitive ability, executive function, and learning/memory. These were significantly associated with CBCL scores in a differential manner but with small effect sizes. These findings set the stage for longitudinal analysis of neurocognitive and psychopathological data from the ABCD cohort as they age into the period of maximal adolescent risk-taking.

Original languageEnglish (US)
Article number100606
JournalDevelopmental Cognitive Neuroscience
Volume36
DOIs
StatePublished - Apr 2019

Bibliographical note

Funding Information:
We thank the families who have participated in this research. We are grateful to Susan Tapert, Ph.D. who has expertly guided the work of ABCD's assessment workgroups, as well as Margie Mejia-Hernandez for her support to the ABCD Workgroup on Neurocognition. This work was supported by the following grants from the United States National Institutes of Health, National Institute on Drug Abuse: 1U24DA041123-01 (Dale), U01DA041120 (Luciana, Barch, Bjork), U01DA041148 (Nagel), U01 DA041156 (Gonzalez), and U01DA041106 (Nixon).

Funding Information:
We thank the families who have participated in this research. We are grateful to Susan Tapert, Ph.D. who has expertly guided the work of ABCD’s assessment workgroups, as well as Margie Mejia-Hernandez for her support to the ABCD Workgroup on Neurocognition. This work was supported by the following grants from the United States National Institutes of Health , National Institute on Drug Abuse : 1U24DA041123-01 (Dale), U01DA041120 (Luciana, Barch, Bjork), U01DA041148 (Nagel), U01 DA041156 (Gonzalez), and U01DA041106 (Nixon).

Publisher Copyright:
© 2018

Keywords

  • Adolescence
  • Child behavior checklist
  • Externalizing
  • Internalizing
  • NIH toolbox
  • Neurocognition
  • Principal components analysis
  • Stress reactivity

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