The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in arabidopsis, encodes a WD40 repeat protein

Amanda R. Walker; Paul A. Davison; Agnese C. Bolognesi-Winfield; Celia M. James; N. Srinivasan; Tom L. Blundell; Jeffrey J. Esch; M. David Marks; John C. Gray

doi:10.1105/tpc.11.7.1337

The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in arabidopsis, encodes a WD40 repeat protein

Amanda R. Walker, Paul A. Davison, Agnese C. Bolognesi-Winfield, Celia M. James, N. Srinivasan, Tom L. Blundell, Jeffrey J. Esch, M. David Marks, John C. Gray

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Abstract

The TRANSPARENT TESTA GLABRA1 (TTG1) locus regulates several developmental and biochemical pathways in Arabidopsis, including the formation of hairs on leaves, stems, and roots, and the production of seed mucilage and anthocyanin pigments. The TTG1 locus has been isolated by positional cloning, and its identity was confirmed by complementation of a ttg1 mutant. The locus encodes a protein of 341 amino acid residues with four WD40 repeats. The protein is similar to AN11, a regulator of anthocyanin biosynthesis in petunia, and more distantly related to those of the β subunits of heterotrimeric G proteins, which suggests a role for TTG1 in signal transduction to downstream transcription factors. The 1.5-kb TTG1 transcript is present in all major organs of Arabidopsis. Sequence analysis of six mutant alleles has identified base changes producing truncations or single amino acid changes in the TTG1 protein.

Original language	English (US)
Pages (from-to)	1337-1349
Number of pages	13
Journal	Plant Cell
Volume	11
Issue number	7
DOIs	https://doi.org/10.1105/tpc.11.7.1337
State	Published - Jul 1999
Externally published	Yes

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Walker, A. R., Davison, P. A., Bolognesi-Winfield, A. C., James, C. M., Srinivasan, N., Blundell, T. L., Esch, J. J., David Marks, M., & Gray, J. C. (1999). The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in arabidopsis, encodes a WD40 repeat protein. Plant Cell, 11(7), 1337-1349. https://doi.org/10.1105/tpc.11.7.1337

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title = "The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in arabidopsis, encodes a WD40 repeat protein",

abstract = "The TRANSPARENT TESTA GLABRA1 (TTG1) locus regulates several developmental and biochemical pathways in Arabidopsis, including the formation of hairs on leaves, stems, and roots, and the production of seed mucilage and anthocyanin pigments. The TTG1 locus has been isolated by positional cloning, and its identity was confirmed by complementation of a ttg1 mutant. The locus encodes a protein of 341 amino acid residues with four WD40 repeats. The protein is similar to AN11, a regulator of anthocyanin biosynthesis in petunia, and more distantly related to those of the β subunits of heterotrimeric G proteins, which suggests a role for TTG1 in signal transduction to downstream transcription factors. The 1.5-kb TTG1 transcript is present in all major organs of Arabidopsis. Sequence analysis of six mutant alleles has identified base changes producing truncations or single amino acid changes in the TTG1 protein.",

author = "Walker, {Amanda R.} and Davison, {Paul A.} and Bolognesi-Winfield, {Agnese C.} and James, {Celia M.} and N. Srinivasan and Blundell, {Tom L.} and Esch, {Jeffrey J.} and {David Marks}, M. and Gray, {John C.}",

year = "1999",

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doi = "10.1105/tpc.11.7.1337",

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AU - Walker, Amanda R.

AU - Davison, Paul A.

AU - Bolognesi-Winfield, Agnese C.

AU - James, Celia M.

AU - Srinivasan, N.

AU - Blundell, Tom L.

AU - Esch, Jeffrey J.

AU - David Marks, M.

AU - Gray, John C.

PY - 1999/7

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AB - The TRANSPARENT TESTA GLABRA1 (TTG1) locus regulates several developmental and biochemical pathways in Arabidopsis, including the formation of hairs on leaves, stems, and roots, and the production of seed mucilage and anthocyanin pigments. The TTG1 locus has been isolated by positional cloning, and its identity was confirmed by complementation of a ttg1 mutant. The locus encodes a protein of 341 amino acid residues with four WD40 repeats. The protein is similar to AN11, a regulator of anthocyanin biosynthesis in petunia, and more distantly related to those of the β subunits of heterotrimeric G proteins, which suggests a role for TTG1 in signal transduction to downstream transcription factors. The 1.5-kb TTG1 transcript is present in all major organs of Arabidopsis. Sequence analysis of six mutant alleles has identified base changes producing truncations or single amino acid changes in the TTG1 protein.

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The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in arabidopsis, encodes a WD40 repeat protein

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