Abstract
The University of Minnesota Pathway Prediction System (UM-PPS, http://umbbd.msi.umn.edu/predict/) is a rule-based system that predicts microbial catabolism of organic compounds. Currently, its knowledge base contains 250 biotransformation rules and five types of metabolic logic entities. The original UM-PPS predicted up to two prediction levels at a time. Users had to choose a predicted product to continue the prediction. This approach provided a limited view of prediction results and heavily relied on manual intervention. The new UM-PPS produces a multi-level prediction within an acceptable time frame, and allows users to view prediction alternatives much more easily as a directed acyclic graph.
Original language | English (US) |
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Pages (from-to) | W406-W411 |
Journal | Nucleic acids research |
Volume | 39 |
Issue number | SUPPL. 2 |
DOIs | |
State | Published - Jul 1 2011 |
Bibliographical note
Funding Information:U.S. National Science Foundation (NSF0543416 to L.E. and L.W.); Minnesota Supercomputing Institute. Funding for open access charge: University of Minnesota.