The use of immunoradiometric assay for the measurement of ACTH in human plasma

James W. Findling, William C. Engeland, Hershel Raff

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Bioassay and immunoassay techniques for the measurement of ACTH in human plasma have provided sensitive and specific results but have also met with some skepticism as to their reliability in some clinical circumstances. The recent development of a supersensitive two-site immunoradiometric assay for ACTH may resolve sole of the limitations of previous assays and greatly facilitate the evaluation of pituitary-adrenal disorders.

Original languageEnglish (US)
Pages (from-to)283-287
Number of pages5
JournalTrends in Endocrinology and Metabolism
Volume1
Issue number6
DOIs
StatePublished - 1990

Bibliographical note

Funding Information:
The studies described were supported in part by grants from the St. Luke’s Foundation to H.R. and DK38951 to W.C.E.

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