TY - JOUR
T1 - Three-dimensional myocardial activation imaging in a rabbit model
AU - Liu, Chenguang
AU - Zhang, Xin
AU - Liu, Zhongming
AU - Pogwizd, Steven M.
AU - He, Bin
PY - 2006/9
Y1 - 2006/9
N2 - This study evaluated a recently developed three-dimensional (3-D) electrocardiographic imaging (3DECI) approach in a closed-chest rabbit model. First, the performance and sensitivity of parameters of 3DECI were evaluated using a geometrically realistic rabbit heart-torso model. Second, a 3-D intracardiac mapping procedure was evaluated based on the heart-torso rabbit model. Third, comparisons were made among the forward-simulated ventricular activation sequence, the activation sequence derived by the intracardiac mapping, and the 3DECI inverse solution. Finally, the present procedures were tested in vivo in a rabbit, in which the relative error between the measured and imaged activation sequence was 0.20 and the localization error was 5.1 mm. The present simulation and experimental results suggest the merits of the 3DECI imaging approach, and the validity of intracardiac mapping as a tool to evaluate the 3DECI.
AB - This study evaluated a recently developed three-dimensional (3-D) electrocardiographic imaging (3DECI) approach in a closed-chest rabbit model. First, the performance and sensitivity of parameters of 3DECI were evaluated using a geometrically realistic rabbit heart-torso model. Second, a 3-D intracardiac mapping procedure was evaluated based on the heart-torso rabbit model. Third, comparisons were made among the forward-simulated ventricular activation sequence, the activation sequence derived by the intracardiac mapping, and the 3DECI inverse solution. Finally, the present procedures were tested in vivo in a rabbit, in which the relative error between the measured and imaged activation sequence was 0.20 and the localization error was 5.1 mm. The present simulation and experimental results suggest the merits of the 3DECI imaging approach, and the validity of intracardiac mapping as a tool to evaluate the 3DECI.
KW - Body surface mapping
KW - Cardiac inverse problem
KW - Cardiac mapping
KW - Electrocardiographic imaging
KW - Intracardiac mapping
UR - http://www.scopus.com/inward/record.url?scp=33747841544&partnerID=8YFLogxK
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U2 - 10.1109/TBME.2006.873701
DO - 10.1109/TBME.2006.873701
M3 - Article
C2 - 16941837
AN - SCOPUS:33747841544
VL - 53
SP - 1813
EP - 1820
JO - IEEE Transactions on Biomedical Engineering
JF - IEEE Transactions on Biomedical Engineering
SN - 0018-9294
IS - 9
M1 - 1673623
ER -