Tissue specific differences in rate limiting factors of glutamate metabolism in enzyme systems of kidney and liver

Ernest Kun, Horace H. Loh, Pierre Volfin

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

In kidney tissue, the quantity of glutamate dehydrogenase limits metabolic flux of glutamate in accordance with predicted linear kinetic coupling of the dehydrogenase with transaminases (cf. 2). In liver tissue, however, control mechanisms of the glutamate system are not related in an obvious manner to the quantity of enzymes for which glutamate is a common substrate.

Original languageEnglish (US)
Pages (from-to)702-706
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume23
Issue number5
DOIs
StatePublished - Jun 13 1966

Bibliographical note

Funding Information:
supported by research grants of the USPHS, and of the NSF, GB-3488. We are indebted to for the availability of ref. 9 prior to its appearance 6. Kun, E. and Volfin, P.: 7. Kun, E. and Achmatowicz, 8. Hermann, G. and Kun, 9. Chance, B., Jamieson, state of reduced pyridine conditions. If 3rd Internat.

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