Toward a heart rate and axillary temperature chronome in schizophrenia: Gauge of disease severity

Mikhail Denisov, Olga Denisova, Franz Halberg, Germaine Cornélissen

Research output: Contribution to journalArticlepeer-review


The heart rate and axillary temperature of 17 patients with schizophrenia were measured every 3 hours during waking for 4 days. In 28 profiles, large inter- and intra-individual variations notwithstanding, relations between the time structures (chronomes) of heart rate and axillary temperature are assessed and further examined from the viewpoint of their bearing on the severity of the patients's condition.

Original languageEnglish (US)
Pages (from-to)13-20
Number of pages8
JournalFunctional Neurology
Issue number1
StatePublished - Mar 1999


  • Axillary temperature
  • Chronome
  • Disease severity
  • Heart rate
  • Schizophrenia

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