A common complaint heard in many quarters is, "Things are moving so fast that it's hard to keep up." A natural response is to narrow our field of expertise to a smaller and smaller sphere. Even then, the rate of knowledge expansion necessitates regular modification; thus, our spheres continue to shrink. What we gain in a semblance of control, we lose in a grasp of the whole. Transdisciplinarity offers an alternative solution to ever-increasing complexity. This article is an exploration of transdisciplinarity and its potential benefits for the profession of nursing.