Transplantation of cholinergic-rich spinal tissue from spontaneously aborted human fetuses into a rodent model of Alzheimer's disease

Y. J. Li, J. A. Conrad, W. C. Low

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The results from this study provided the first piece of evidence that intrahippocampal transplants of cholinergic-rich spinal grafts derived from a human fetus can ameliorate the performance of fornix lesioned rats in both spatial reference memory and spatial navigation tasks. Although many questions remain to be answered, these results point to the therapeutic potential of human fetus-derived cholinergic-rich grafts in treating spatial memory impairments.

Original languageEnglish (US)
Pages (from-to)3336-3337
Number of pages2
JournalTransplantation proceedings
Volume26
Issue number6
StatePublished - 1994

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