Transposons for cancer gene discovery: Sleeping beauty and beyond

Lara S. Collier; David A. Largaespada

doi:10.1186/gb-2007-8-s1-s15

Transposons for cancer gene discovery: Sleeping beauty and beyond

Lara S. Collier, David A. Largaespada

Pediatrics - Hematology

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping Beauty for cancer genetic studies and the potential use of additional transposable elements for somatic mutagenesis.

Original language	English (US)
Article number	S15
Journal	Genome biology
Volume	8
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1186/gb-2007-8-s1-s15
State	Published - Oct 31 2007

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title = "Transposons for cancer gene discovery: Sleeping beauty and beyond",

abstract = "The use of Sleeping Beauty transposons as somatic mutagens to discover cancer genes in hematopoietic tumors and sarcomas has been documented. Here, we discuss the future of Sleeping Beauty for cancer genetic studies and the potential use of additional transposable elements for somatic mutagenesis.",

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Transposons for cancer gene discovery: Sleeping beauty and beyond

Abstract

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