Treatment with sildenafil for the healing of refractory skin ulcerations in the antiphospholipid syndrome

E. Gertner

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Nonhealing skin ulceration is a cutaneous manifestation of the antiphospholipid syndrome (APS) and is associated with thrombosis of small dermal vessels. Numerous therapies have been described but are either ineffective or require a prolonged course of treatment with potential complications. We describe the efficacy of sildenafil, a phosphodiesterase inhibitor, in the treatments of such ulcers.

Original languageEnglish (US)
Pages (from-to)133-135
Number of pages3
JournalLupus
Volume12
Issue number2
DOIs
StatePublished - Mar 5 2003

Keywords

  • Antiphospholipid syndrome
  • Sildenafil
  • Skin ulcerations

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