Trends in coded causes of death following definite myocardial infarction and therole of competing risks: The minnesota heart survey (MHS)

Jim Pankow, Paul G. McGovern, J. Michael Sprafka, David R Jacobs Jr, Henry Blackburn

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

We investigated possible differences over time in underlying causes of death among validated definite myocardial infarction cases who were discharged following an index hospitalization in 1970, 1980, and 1985 in the Twin Cites, MN. No changes were observed in underlying causes of death assigned to patients who died prior to discharge in the 3 years. Among in-hospital survivors of definite MI, however, age-adjusted rates of death from non-cardiovascular causes more than doubled between 1970 and 1985 (P < 0.01). More specifically, mortality rates for diabetes mellitus increased significantly from 1970 to 1985 (P < 0.05), while those for neoplasms and diseases of the respiratory system increased non-significantly. Whether these data are the result of artifactual changes in cause of death assignment or real changes in disease severity and comorbidity, these trends in long-term death following acute MI may have had a modest impact on reported community-wide coronary heart disease mortality rates.

Original languageEnglish (US)
Pages (from-to)1051-1060
Number of pages10
JournalJournal of Clinical Epidemiology
Volume47
Issue number9
DOIs
StatePublished - Sep 1994

Keywords

  • Cause of death
  • Diabetes mellitus
  • Mortality
  • Myocardial infarction
  • Survival
  • Trends

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