TY - JOUR
T1 - Trends in myocardial infarction rates and case fatality by anatomical location in four united states communities, 1987 to 2008 (from the atherosclerosis risk in communities study)
AU - Newman, Jonathan D.
AU - Shimbo, Daichi
AU - Baggett, Chris
AU - Liu, Xiaoxi
AU - Crow, Richard
AU - Abraham, Joellyn M.
AU - Loehr, Laura R.
AU - Wruck, Lisa M.
AU - Folsom, Aaron R.
AU - Rosamond, Wayne D.
N1 - Funding Information:
The ARIC Study is carried out as a collaborative study supported by the National Heart, Lung, and Blood Institute contracts N01-HC-55015 , N01- HC-55016 , N01-HC-55018 , N01-HC-55019 , N01-HC-55020 , N01-HC-55021 , and N01-HC-55022 .
PY - 2013/12/1
Y1 - 2013/12/1
N2 - Although the incidence of and mortality after ST-segment elevation myocardial infarction (STEMI) is decreasing, time trends in anatomical location of STEMI and associated short-term prognosis have not been examined in a population-based community study. We determined 22-year trends in age- and race-adjusted gender-specific incidences and 28-day case fatality of hospitalized STEMI by anatomic infarct location among a stratified random sample of 35- to 74-year-old residents of 4 communities in the Atherosclerosis Risk in Communities study. STEMI infarct location was assessed by 12-lead electrocardiograms from the hospital record and was coded as anterior, inferior, lateral, and multilocation STEMIs using the Minnesota code. From 1987 to 2008, a total of 4,845 patients had an incident STEMI; 37.2% were inferior STEMI, 32.8% were anterior, 16.8% occurred in multiple infarct locations, and 13.2% were lateral STEMI. For inferior, anterior, and lateral STEMIs in both men and women, significant decreases were observed in the age-adjusted annual incidence and the associated 28-day case fatality. In contrast, for STEMI in multiple infarct locations, neither the annual incidence nor the 28-day case fatality changed over time. The age- and race-adjusted annual incidence and associated 28-day case fatality of STEMI in anterior, inferior, and lateral infarct locations decreased during 22 years of surveillance; however, no decrease was observed for STEMI in multiple infarct locations. In conclusion, our findings suggest that there is room for improvement in the care of patients with multilocation STEMI.
AB - Although the incidence of and mortality after ST-segment elevation myocardial infarction (STEMI) is decreasing, time trends in anatomical location of STEMI and associated short-term prognosis have not been examined in a population-based community study. We determined 22-year trends in age- and race-adjusted gender-specific incidences and 28-day case fatality of hospitalized STEMI by anatomic infarct location among a stratified random sample of 35- to 74-year-old residents of 4 communities in the Atherosclerosis Risk in Communities study. STEMI infarct location was assessed by 12-lead electrocardiograms from the hospital record and was coded as anterior, inferior, lateral, and multilocation STEMIs using the Minnesota code. From 1987 to 2008, a total of 4,845 patients had an incident STEMI; 37.2% were inferior STEMI, 32.8% were anterior, 16.8% occurred in multiple infarct locations, and 13.2% were lateral STEMI. For inferior, anterior, and lateral STEMIs in both men and women, significant decreases were observed in the age-adjusted annual incidence and the associated 28-day case fatality. In contrast, for STEMI in multiple infarct locations, neither the annual incidence nor the 28-day case fatality changed over time. The age- and race-adjusted annual incidence and associated 28-day case fatality of STEMI in anterior, inferior, and lateral infarct locations decreased during 22 years of surveillance; however, no decrease was observed for STEMI in multiple infarct locations. In conclusion, our findings suggest that there is room for improvement in the care of patients with multilocation STEMI.
UR - http://www.scopus.com/inward/record.url?scp=84887907823&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887907823&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2013.07.037
DO - 10.1016/j.amjcard.2013.07.037
M3 - Article
C2 - 24063834
AN - SCOPUS:84887907823
SN - 0002-9149
VL - 112
SP - 1714
EP - 1719
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 11
ER -