TY - JOUR
T1 - Two-year clinical evaluation of proanthocyanidins added to a two-step etch-and-rinse adhesive
AU - de Souza, Lidiane Costa
AU - Rodrigues, Nara Sousa
AU - Cunha, Diana Araújo
AU - Feitosa, Victor Pinheiro
AU - Santiago, Sérgio Lima
AU - Reis, Alessandra
AU - Loguercio, Alessandro Dourado
AU - Matos, Thalita de Paris
AU - Saboia, Vicente de Paulo Aragão
AU - Perdigão, Jorge
N1 - Funding Information:
This investigation was supported by research grants from FUNCAP (Grant# CI3-0093-000670100/14 ) and CAPES (scholarship). The authors would like to thank the generous donations of resin composite Empress Direct by Ivoclar Vivadent.
Publisher Copyright:
© 2018 Elsevier Ltd
PY - 2019/2
Y1 - 2019/2
N2 - Objective: To compare the clinical behavior of Proanthocyanidins (PA)-free and PA-containing two-step etch-and-rinse adhesive used underneath resin composite restorations in non-carious cervical lesions (NCCLs) over a 6- (6 M) and 24-month (24 M) period. Methods: 135 restorations were randomly placed in 45 subjects. The NCCLs were conditioned (37% phosphoric acid for 15 s) and distributed into 3 groups: Control (EX0) - ExciTE F (Ivoclar Vivadent) adhesive applied following the manufacturer's recommendations; EX2 and EX5 – 2 wt% and 5 wt% of PA were added to ExciTE F, respectively, and applied as in EX0. Resin composite was placed incrementally and light-cured. The restorations were evaluated at baseline, 6 M and 24 M, using FDI and USPHS criteria. Statistical analyses were performed using Friedman and Wilcoxon tests (α = 0.05). Results: The retention rates were 98% (95% confidence interval 88–99%) for EX0, 92% (80–97%) for EX2; and 85% (72–93%) for EX5 at 6 M. A significant difference was found only for EX5 at 6 M when compared with the respective baseline findings (p = 0.03) and when compared with EX0 and EX2 (p = 0.001) at 6 M. After 24 M, the retention rates were 98% (88–99%) for EX0, 73% (59–84%) for EX2, and 71% (56–82%) for EX5. Only EX0 did not result in significant difference in retention rate at 24 M when compared with baseline but showed a significant higher retention rate when compared with those of EX2 and EX5 (p = 0.001). Conclusion: Adding proanthocyanidins to the adhesive solution jeopardized the retention of composite resins restorations in non-carious cervical lesions after 24 months. Clinical relevance: In spite of being user-friendlier than when used separately, the incorporation of proanthocyanidins into the adhesive solution impairs the longevity of composite restorations.
AB - Objective: To compare the clinical behavior of Proanthocyanidins (PA)-free and PA-containing two-step etch-and-rinse adhesive used underneath resin composite restorations in non-carious cervical lesions (NCCLs) over a 6- (6 M) and 24-month (24 M) period. Methods: 135 restorations were randomly placed in 45 subjects. The NCCLs were conditioned (37% phosphoric acid for 15 s) and distributed into 3 groups: Control (EX0) - ExciTE F (Ivoclar Vivadent) adhesive applied following the manufacturer's recommendations; EX2 and EX5 – 2 wt% and 5 wt% of PA were added to ExciTE F, respectively, and applied as in EX0. Resin composite was placed incrementally and light-cured. The restorations were evaluated at baseline, 6 M and 24 M, using FDI and USPHS criteria. Statistical analyses were performed using Friedman and Wilcoxon tests (α = 0.05). Results: The retention rates were 98% (95% confidence interval 88–99%) for EX0, 92% (80–97%) for EX2; and 85% (72–93%) for EX5 at 6 M. A significant difference was found only for EX5 at 6 M when compared with the respective baseline findings (p = 0.03) and when compared with EX0 and EX2 (p = 0.001) at 6 M. After 24 M, the retention rates were 98% (88–99%) for EX0, 73% (59–84%) for EX2, and 71% (56–82%) for EX5. Only EX0 did not result in significant difference in retention rate at 24 M when compared with baseline but showed a significant higher retention rate when compared with those of EX2 and EX5 (p = 0.001). Conclusion: Adding proanthocyanidins to the adhesive solution jeopardized the retention of composite resins restorations in non-carious cervical lesions after 24 months. Clinical relevance: In spite of being user-friendlier than when used separately, the incorporation of proanthocyanidins into the adhesive solution impairs the longevity of composite restorations.
KW - Clinical trial
KW - Dentin-bonding agents
KW - Longevity
KW - Non-carious cervical lesions
KW - Proanthocyanidins
UR - http://www.scopus.com/inward/record.url?scp=85059226023&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85059226023&partnerID=8YFLogxK
U2 - 10.1016/j.jdent.2018.12.012
DO - 10.1016/j.jdent.2018.12.012
M3 - Article
C2 - 30594631
AN - SCOPUS:85059226023
SN - 0300-5712
VL - 81
SP - 7
EP - 16
JO - Journal of Dentistry
JF - Journal of Dentistry
ER -