Ultrasound guided subcostal transversus abdominis plane (TAP) infiltration with liposomal bupivacaine for patients undergoing robotic assisted hysterectomy: A prospective randomized controlled study

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47 Scopus citations

Abstract

Introduction Optimal pain control after major surgery contributes to a patient's recovery and satisfaction. The use of liposomal bupivacaine in subcostal transversus abdominis plane (TAP) blocks for postoperative pain control after robot assisted abdominal surgery has yet to be studied. Methods We conducted a prospective randomized controlled observer-blinded study comparing bilateral subcostal TAP blocks with bupivacaine to bilateral subcostal TAP blocks with liposomal bupivacaine. These were performed prior to the patient undergoing robot assisted hysterectomy. The patients' pain scores, opioid use, side effects, and satisfaction were followed for 72 h after injection. Results Total opioid use in the first 72 h after injection was significantly decreased in the group that received liposomal bupivacaine compared to bupivacaine. Patients in the liposomal bupivacaine group had significantly lower maximal pain scores at all time periods studied as well as decreased incidence of nausea/vomiting. There was a trend toward decreased length of stay in the liposomal bupivacaine group. Conclusion Subcostal TAP blocks with liposomal bupivacaine decreased the total opioid requirement for the first 72 h after robot assisted hysterectomy when compared to subcostal TAP blocks with bupivacaine.

Original languageEnglish (US)
Pages (from-to)609-613
Number of pages5
JournalGynecologic oncology
Volume138
Issue number3
DOIs
StatePublished - Sep 1 2015

Bibliographical note

Funding Information:
Jacob Hutchins is on the speaker's bureau, is a consultant, and has received grant funding from Pacira Pharmaceuticals. None of the other authors have anything to disclose.

Publisher Copyright:
© 2015 Elsevier Inc.

Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.

Keywords

  • Acute pain
  • Hysterectomy
  • Liposomal bupivacaine
  • Post-operative pain
  • Robotic
  • Transversus abdominis plane

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