Ultrastructural changes in muscles of tumor-bearing mice

Barbara A. Zweber; A. Awad Essam; Gerald J. Haiden; Majid Abaasnezhad; Athanasios Theologides

doi:10.1159/000225714

Ultrastructural changes in muscles of tumor-bearing mice

Barbara A. Zweber, A. Awad Essam, Gerald J. Haiden, Majid Abaasnezhad, Athanasios Theologides

Medicine - Hematology, Oncology, Transplant

Research output: Contribution to journal › Article › peer-review

Abstract

A transplanted mammary carcinoma or a transplanted methylcholanthrene-induced tumor implanted subcutaneously on the animal’s back caused dilation of the sarcoplasmic reticulum and apparent protein loss in the white fibers only of the gastrocnemius muscle of C3H female mice. The changes were more pronounced in old mice. Ultrastructural changes were not observed in the red fibers of the gastrocnemius, in the heart, or in the diaphragm. These remote tumor effects correlate well with biochemical alterations in white fibers.

Original language	English (US)
Pages (from-to)	155-158
Number of pages	4
Journal	Oncology (Switzerland)
Volume	40
Issue number	2
DOIs	https://doi.org/10.1159/000225714
State	Published - 1983

Keywords

Asthenia
Cancer host
Muscles
Sarcoplasmic reticulum

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Ultrastructural changes in muscles of tumor-bearing mice",

abstract = "A transplanted mammary carcinoma or a transplanted methylcholanthrene-induced tumor implanted subcutaneously on the animal{\textquoteright}s back caused dilation of the sarcoplasmic reticulum and apparent protein loss in the white fibers only of the gastrocnemius muscle of C3H female mice. The changes were more pronounced in old mice. Ultrastructural changes were not observed in the red fibers of the gastrocnemius, in the heart, or in the diaphragm. These remote tumor effects correlate well with biochemical alterations in white fibers.",

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AU - Haiden, Gerald J.

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AU - Theologides, Athanasios

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Y1 - 1983

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AB - A transplanted mammary carcinoma or a transplanted methylcholanthrene-induced tumor implanted subcutaneously on the animal’s back caused dilation of the sarcoplasmic reticulum and apparent protein loss in the white fibers only of the gastrocnemius muscle of C3H female mice. The changes were more pronounced in old mice. Ultrastructural changes were not observed in the red fibers of the gastrocnemius, in the heart, or in the diaphragm. These remote tumor effects correlate well with biochemical alterations in white fibers.

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KW - Muscles

KW - Sarcoplasmic reticulum

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Ultrastructural changes in muscles of tumor-bearing mice

Abstract

Keywords

UN SDGs

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