Abstract
Bacteria realize the ability to communicate by production of quorum sensing (QS) molecules called autoinducers, which regulate the physiological activities in their ecological niches. The oral cavity could be a potential area for the presence of QS bacteria. In this study, we report the isolation of a QS bacterial isolate C10B from dentine caries. Preliminary screening using Chromobacterium violaceum CV026 biosensor showed that isolate C10B was able to produce N-acylhomoserine lactones (AHLs). This bacterium was further identified as a member of Burkholderia, an opportunistic pathogen. The isolated Burkholderia sp. was confirmed to produce N-hexanoyl-L-homoserine lactone (C6-HSL), N-octanoyl-L-homoserine lactone (C8-HSL), N-decanoyl-L-homoserine lactone (C10-HSL) and N-dodecanoyl-L-homoserine lactone (C12-HSL).
Original language | English (US) |
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Pages (from-to) | 8940-8949 |
Number of pages | 10 |
Journal | Sensors (Switzerland) |
Volume | 14 |
Issue number | 5 |
DOIs | |
State | Published - May 21 2014 |
Externally published | Yes |
Keywords
- Chromobacterium violaceum CV026
- Dentine caries
- N-decanoyl-L-homoserine lactone (C10-HSL)
- N-dodecanoyl-L-homoserine lactone (C12-HSL)
- N-hexanoyl-L-homoserine lactone (C6-HSL)
- N-octanoyl-L-homoserine lactone (C8-HSL)
- Oral cavity
- Quorum sensing (QS)