Use of an inspiratory impedance threshold valve during cardiopulmonary resuscitation: A progress report

Keith Lurie, Wolfgang Voelckel, Patrick Plaisance, Todd Zielinski, Scott McKnite, Darrel Kor, Atsushi Sugiyama, Pamela Sukhum

Research output: Contribution to journalArticlepeer-review

71 Scopus citations


Building upon studies on the mechanism of active compression-decompression (ACD) cardiopulmonary resuscitation, a new inspiratory impedance threshold valve has been developed to enhance the return of blood to the thorax during the decompression phase of CPR. Use of this device results in a greater negative intrathoracic pressure during chest wall decompression. This leads to improved vital organ perfusion during both standard and ACD CPR. Animal and human studies suggest that this simple device increases cardiopulmonary circulation by harnessing more efficiently the kinetic energy of the outward movement of the chest wall during standard CPR or active chest wall decompression. When used in conjunction with ACD CPR during clinical evaluation, addition of the impedance valve resulted in sustained systolic pressures of greater than 100 mmHg and diastolic pressures of greater than 55 mmHg. The new valve may be beneficial in patients in asystole or shock refractory ventricular fibrillation, when enhanced return of blood flow to the chest is needed to 'prime the pump'. The potential long-term benefits of this new valve remain under investigation. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish (US)
Pages (from-to)219-230
Number of pages12
Issue number3
StatePublished - May 2000


  • Active compression-decompression (ACD)
  • Cardiopulmonary resuscitation
  • Inspiratory impedance threshold valve

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