Use of botulinum toxin type B for the treatment of detrusor hyperreflexia in a patient with multiple sclerosis: A case report

Dennis D Dykstra, Jon L Pryor, Gary Goldish

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

We describe a patient with multiple sclerosis (MS) who had detrusor hyperreflexia that was not responsive to oral medications or clean intermittent catheterization. This patient was successfully treated with 2 separate injections of botulinum toxin type B into the bladder. The results of the treatment lasted 4 months and there were no side effects. A cystometrogram (CMG) done before the botulinum toxin type B injections showed significant detrusor instability. A repeat CMG months later showed no detrusor instability. To our knowledge, this is the first reported successful use of botulinum toxin type B in a patient with detrusor hyperreflexia from MS.

Original languageEnglish (US)
Pages (from-to)1399-1400
Number of pages2
JournalArchives of Physical Medicine and Rehabilitation
Volume84
Issue number9
DOIs
StatePublished - Sep 1 2003

Keywords

  • Botulinum toxins
  • Case report
  • Hyperreflexia
  • Multiple sclerosis
  • Rehabilitation

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