Use of mucosal immunization with porcine zona pellucida (PZP) in mice and rabbits

Brent J. Martin; Mark A. Suckow; William R. Wolter; Thomas Berger; John W. Turner

doi:10.1016/j.anireprosci.2005.09.007

Use of mucosal immunization with porcine zona pellucida (PZP) in mice and rabbits

Brent J. Martin, Mark A. Suckow, William R. Wolter, Thomas Berger, John W. Turner

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Rabbits (Oryctolagus cuniculus) and two strains of mice (Mus musculus, one inbred and one outbred) were immunized against porcine zona pellucida (PZP) antigen. Alginate microspheres or cholera toxin B were used alone or in combination when mucosal immunization routes were used. Serum antibody responses and fertility were assessed. Neither rabbit or mouse groups immunized by mucosal routes generated significant antibody responses to PZP as compared to parenteral immunization (ANOVA, P > 0.05). The study shows that porcine zona pellucida is not an effective mucosal antigen in small mammals.

Original language	English (US)
Pages (from-to)	372-378
Number of pages	7
Journal	Animal reproduction science
Volume	93
Issue number	3-4
DOIs	https://doi.org/10.1016/j.anireprosci.2005.09.007
State	Published - Jul 2006
Externally published	Yes

Keywords

Alginate microsphere
Mouse
Mucosal immunity
PZP
Porcine zona pellucida
Rabbit

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Use of mucosal immunization with porcine zona pellucida (PZP) in mice and rabbits",

abstract = "Rabbits (Oryctolagus cuniculus) and two strains of mice (Mus musculus, one inbred and one outbred) were immunized against porcine zona pellucida (PZP) antigen. Alginate microspheres or cholera toxin B were used alone or in combination when mucosal immunization routes were used. Serum antibody responses and fertility were assessed. Neither rabbit or mouse groups immunized by mucosal routes generated significant antibody responses to PZP as compared to parenteral immunization (ANOVA, P > 0.05). The study shows that porcine zona pellucida is not an effective mucosal antigen in small mammals.",

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AU - Martin, Brent J.

AU - Suckow, Mark A.

AU - Wolter, William R.

AU - Berger, Thomas

AU - Turner, John W.

PY - 2006/7

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KW - Alginate microsphere

KW - Mouse

KW - Mucosal immunity

KW - PZP

KW - Porcine zona pellucida

KW - Rabbit

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ER -

Use of mucosal immunization with porcine zona pellucida (PZP) in mice and rabbits

Abstract

Keywords

UN SDGs

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