Use of the electrical aerosol detector as an indicator for the total particle surface area deposited in the lung

William E. Wilson, Hee Siew Han, John Stanek, Jay Turner, Da Ren Chen, David Y Pui

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

Because of recent concerns about the health effects of ultrafine particles, we have been examining techniques for measuring particles in the 0.003 to 0.01 μm size range. In an earlier study, we found that the charge accepted by particles, as measured by the Electrical Aerosol Detector (BAD), is related to the 1.16 power of the mobility diameter. An inspection of the pattern of particle deposition in the lung, as a function of particle size, suggests that the EAD measurement might be a useful indicator of the surface area of particles deposited in the lung. In this study, we calculate the amount of particle surface area deposited in the lung, as a function of particle size, using atmospheric particle size distributions measured over a nine-month period at the St. Louis Supersite. The correlation between the amount of surface area deposited in the lung and powers of the mobility diameter, D X, for X = 0 to X = 3 was found to be high for X = 1.1 to 1.6. In addition, the correlation coefficients of the EAD signal and the amount of particle surface area deposited in the TB and A regions are in the range of 0.91-0.97 and 0.87-0.97, respectively. These high correlation coefficients suggest that EAD could serve as an indicator of particle surface area deposited in the lungs for use in exposure and epidemiological studies of human health effects of atmospheric particles.

Original languageEnglish (US)
Title of host publicationSymposium on Air Quality Measurement Methods and Technology 2004
Pages173-186
Number of pages14
StatePublished - Dec 1 2004
EventSymposium on Air Quality Measurement Methods and Technology 2004 - Cary, NC, United States
Duration: Apr 20 2004Apr 22 2004

Publication series

NameSymposium on Air Quality Measurement Methods and Technology 2004

Other

OtherSymposium on Air Quality Measurement Methods and Technology 2004
Country/TerritoryUnited States
CityCary, NC
Period4/20/044/22/04

Keywords

  • Active surface area
  • Electrical aerosol detector
  • Participate matter
  • Particle charge
  • Particle deposition
  • Surface area

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