Validation of whole blood rapid diagnosis test for hepatitis b

Jose D. Debes, Gertine van Oord, Andre Boonstra

Research output: Contribution to journalLetterpeer-review

Abstract

We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all geno-types other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensi-tivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.

Original languageEnglish (US)
Article number53
JournalAnnals of global health
Volume86
Issue number1
DOIs
StatePublished - 2020

Bibliographical note

Funding Information:
This work was supported the Robert Wood Johnson Foundation, AFMDP, Mitialto Foundation and NIH-NCI R21 CA215883-01A1 all to JDD. Funding sponsors had no role in the production of this manuscript.

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