Validation of whole blood rapid diagnosis test for hepatitis b

Jose D. Debes; Gertine van Oord; Andre Boonstra

doi:10.5334/aogh.2866

Validation of whole blood rapid diagnosis test for hepatitis b

Jose D. Debes, Gertine van Oord, Andre Boonstra

Medicine - Infectious Disease and International

Research output: Contribution to journal › Letter › peer-review

Abstract

We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all geno-types other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensi-tivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.

Original language	English (US)
Article number	53
Journal	Annals of global health
Volume	86
Issue number	1
DOIs	https://doi.org/10.5334/aogh.2866
State	Published - 2020

Bibliographical note

Publisher Copyright:
© 2020 The Author(s).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access

10.5334/aogh.2866

OpenUrl availability

Full text

Cite this

@article{25625a4257bb466e93b9eef4f2a6db5b,

title = "Validation of whole blood rapid diagnosis test for hepatitis b",

abstract = "We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all geno-types other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensi-tivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.",

author = "Debes, {Jose D.} and {van Oord}, Gertine and Andre Boonstra",

note = "Publisher Copyright: {\textcopyright} 2020 The Author(s).",

year = "2020",

doi = "10.5334/aogh.2866",

language = "English (US)",

volume = "86",

journal = "Annals of global health",

issn = "0027-2507",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Validation of whole blood rapid diagnosis test for hepatitis b

AU - Debes, Jose D.

AU - van Oord, Gertine

AU - Boonstra, Andre

PY - 2020

Y1 - 2020

N2 - We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all geno-types other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensi-tivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.

AB - We recently published a report validating point-of-care rapid diagnostic tests (RDT) for the diagnosis of Hepatitis B virus (HBV) infection in serum. In the current report, we validated a whole-blood RDT for HBsAg in the form of a test-strip. The test was validated in 55 HBV positive individuals across all geno-types other than F, and in 20 HBV negative individuals in the Netherlands. The RDT showed 100% sensi-tivity and specificity. The low cost and use in whole blood allows this RDT to be useful in resource-limited locations, further validation in such settings will be of importance.

UR - http://www.scopus.com/inward/record.url?scp=85085527851&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85085527851&partnerID=8YFLogxK

U2 - 10.5334/aogh.2866

DO - 10.5334/aogh.2866

M3 - Letter

C2 - 32477889

AN - SCOPUS:85085527851

SN - 0027-2507

VL - 86

JO - Annals of global health

JF - Annals of global health

IS - 1

M1 - 53

ER -

Validation of whole blood rapid diagnosis test for hepatitis b

Abstract

Bibliographical note

UN SDGs

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this