Vascular compliance in hypertension

Stanley M Finkelstein, William Feske, James Mock, Peter Carlyle, Thomas Rector, Spencer Kubo, Jay N Cohn

Research output: Contribution to conferencePaperpeer-review

6 Scopus citations

Abstract

Pulse contour analysis was used to determine systemic arterial vascular compliance in hypertensive (HT) and normotensive (NT) subjects. In seven hypertensives aged 43-58 yrs (mean age 52.1 ± 5.5 yrs) and seven normotensives aged 33-59 yrs (mean age 43.7 ± 9.9 yrs) both large artery (C1) and distal arterial (C2) compliance were determined from a peripheral arterial pressure waveform and cardiac output. Age differences were not statistically significant. Mean arterial pressure was 29% higher in HT (p < 0.001). Cardiac output was 12% higher and heart rate was 6% lower in HT, but these differences were not significant. Systemic vascular resistance was 17% higher in HT (NS), while proximal and distal arterial compliance were 15% and 70% lower, respectively, in HT compared to NT. Only the difference in C2 was significant (p < 0.02). Thus, distal vascular compliance may be a clinically useful parameter for evaluating hypertensive subjects before and during therapeutic intervention.

Original languageEnglish (US)
Pages241-242
Number of pages2
StatePublished - Nov 1 1988
EventProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society - New Orleans, LA, USA
Duration: Nov 4 1988Nov 7 1988

Other

OtherProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityNew Orleans, LA, USA
Period11/4/8811/7/88

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