Purpose: To evaluate change in best corrected visual acuity (BCVA) during the second decade of life and the effects of albinism type and extraocular muscle surgery on BCVA in children with albinism. Methods: In this retrospective longitudinal study, 41 patients with albinism with clinic visits recording binocular BCVA at least once between the ages of 10 and 13 years (visit A) and again between the ages of 17 and 20 years (visit B) were included. Type of albinism, age at each visit, and interval eye muscle surgeries were recorded for each patient. Results: Forty (98%) patients showed BCVA improvement or stability between visits A and B. There was no significant effect of interval extraocular muscle surgery on BCVA. Those carrying either a clinically presumed or moleculary confirmed diagnosis of oculocutaneous albinism types 1B and 2 had the best visual outcomes, consistent with previous studies. Conclusions: In the majority of patients with albinism, significant improvement in BCVA occurs during the second decade of life. Extraocular muscle surgery was not a significant factor in BCVA improvement in albinism. Overall, the assessments support the finding of improvement of visual acuity in children with albinism at earlier ages and provide new information beneficial in predicting visual outcomes in the second decade of life.
Bibliographical noteFunding Information:
From the Department of Ophthalmology and Visual Neurosciences, Medical School (BKM, AMH, CGS), the Department of Biostatistical Design and Analysis Center (JEC), the Biostatistics Division, School of Public Health (JEC), and the Department of Pediatrics, Medical School (CGS), University of Minnesota, Minneapolis, Minnesota. Submitted: June 22, 2017; Accepted: September 28, 2017 Supported in part by an unrestricted grant to the Department of Ophthalmology and Visual Neurosciences at the University of Minnesota from Research to Prevent Blindness, Inc., New York, New York. The authors have no financial or proprietary interest in the materials presented herein. Correspondence: C. Gail Summers, MD, Minnesota Lions Children’s Eye Clinic, 701 25th Avenue South, #300, Minneapolis, MN 55454. E-mail: email@example.com doi:10.3928/01913913-20180327-02
Supported in part by an unrestricted grant to the Department of Ophthalmology and Visual Neurosciences at the University of Minnesota from Research to Prevent Blindness, Inc., New York, New York. The authors have no financial or proprietary interest in the materials presented herein
© 2018 Healio.