This review is divided into sections based on three of the questions which this research has addressed. First, how significant are local influences in the histotypic differentiation of nervous tissue? Second, when a tissue is placed in an anomalous location, is it still able to form appropriate axonal connections with the host CNS, and is there a limit to a tissue's ability to form connections when it is placed at increasing distances from its normal target nuclei? Third, does the age of the recipient at the time of transplantation influence the differentiation and connections exhibited by the transplants? A fourth line of investigation, examining factors that play a role in guiding the growth of axons, is addressed in a subsequent chapter.
|Original language||English (US)|
|Number of pages||17|
|Journal||Fernstrom Foundation Series|
|State||Published - Jan 1 1985|