When ligand becomes receptor — Tolerance via B7 signaling on DCs

Erik B. Finger; Jeffrey A. Bluestone

doi:10.1038/ni1102-1056

When ligand becomes receptor — Tolerance via B7 signaling on DCs

Erik B. Finger, Jeffrey A. Bluestone

Surgery

Research output: Contribution to journal › Comment/debate › peer-review

104 Scopus citations

Abstract

In summary, Grohmann et al. have described a pathway of tolerance induction that focuses on the role of the APC rather than the T cell as the principle discriminator of function. Although it is likely that this pathway is only one of several alternative modes of tolerance, it has potentially great therapeutic implications for transplantation, autoimmunity and tumor immunology.

Original language	English (US)
Pages (from-to)	1056-1057
Number of pages	2
Journal	Nature Immunology
Volume	3
Issue number	11
DOIs	https://doi.org/10.1038/ni1102-1056
State	Published - Nov 2002

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When ligand becomes receptor — Tolerance via B7 signaling on DCs

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