Research output per year
Research output per year
Research output
- 17 Article
- 17 results
Search results
-
2023
A tri-specific killer engager against mesothelin targets NK cells towards lung cancer
Kennedy, P. R., Vallera, D. A., Ettestad, B., Hallstrom, C., Kodal, B., Todhunter, D. A., Bendzick, L., Hinderlie, P., Walker, J. T., Pulkrabek, B., Pastan, I., Kratzke, R. A., Fujioka, N., Miller, J. S. & Felices, M., 2023, In: Frontiers in immunology. 14, 1060905.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2020
Impact of repeated cycles of EGF bispecific angiotoxin (eBAT) administered at a reduced interval from doxorubicin chemotherapy in dogs with splenic haemangiosarcoma
Borgatti, A., Fieberg, A., Winter, A. L., Stuebner, K., Taras, E., Todhunter, D., Masyr, A., Rendhal, A., Vallera, D. A., Koopmeiners, J. S. & Modiano, J. F., Dec 2020, In: Veterinary and Comparative Oncology. 18, 4, p. 664-674 11 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2018
Development of a deimmunized bispecific immunotoxin dDT2219 against B-cell malignancies
Schmohl, J. U., Todhunter, D., Taras, E., Bachanova, V. & Vallera, D. A., Jan 6 2018, In: Toxins. 10, 1, 32.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Targeting EGFR and uPAR on human rhabdomyosarcoma, osteosarcoma, and ovarian adenocarcinoma with a bispecific ligand-directed toxin
Oh, F., Todhunter, D., Taras, E., Vallera, D. A. & Borgatti, A., 2018, In: Clinical Pharmacology: Advances and Applications. 10, p. 113-121 9 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2017
Safe and effective sarcoma therapy through bispecific targeting of EGFR and uPAR
Borgatti, A., Koopmeiners, J. S., Sarver, A. L., Winter, A. L., Stuebner, K., Todhunter, D., Rizzardi, A. E., Henriksen, J. C., Schmechel, S., Forster, C. L., Kim, J. H., Froelich, J., Walz, J., Henson, M. S., Breen, M., Lindblad-Toh, K., Oh, F., Pilbeam, K., Modiano, J. F. & Vallera, D. A., May 1 2017, In: Molecular Cancer Therapeutics. 16, 5, p. 956-965 10 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
2016
Tetraspecific scFv construct provides NK cell mediated ADCC and self-sustaining stimuli via insertion of IL-15 as a cross-linker
Schmohl, J. U., Felices, M., Todhunter, D., Taras, E., Miller, J. S. & Vallera, D. A., 2016, In: Oncotarget. 7, 45, p. 73830-73844 15 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
2015
Mutagenic deimmunization of diphtheria toxin for use in biologic drug development
Schmohl, J. U., Todhunter, D., Oh, S. & Vallera, D. A., Oct 10 2015, In: Toxins. 7, 10, p. 4067-4082 16 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2012
A deimmunized bispecific ligand-directed toxin that shows an impressive anti-pancreatic cancer effect in a systemic nude mouse orthotopic model
Oh, S., Todhunter, D. A., Panoskaltsis-Mortari, A., Buchsbaum, D. J., Toma, S. & Vallera, D. A., Jul 2012, In: Pancreas. 41, 5, p. 789-796 8 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production
Gleason, M. K., Verneris, M. R., Todhunter, D. A., Zhang, B., McCullar, V., Zhou, S. X., Panoskaltsis-Mortari, A., Weiner, L. M., Vallera, D. A. & Miller, J. S., Dec 2012, In: Molecular Cancer Therapeutics. 11, 12, p. 2674-2684 11 p.Research output: Contribution to journal › Article › peer-review
Open Access193 Scopus citations -
2009
Intracranial elimination of human glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery
Oh, S., Ohlfest, J. R., Todhunter, D. A., Vallera, V. D., Hall, W. A., Chen, H. & Vallera, D. A., Dec 2009, In: Journal of neuro-oncology. 95, 3, p. 331-342 12 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
2007
Intracranial therapy of glioblastoma with the fusion protein DTAT in immunodeficient mice
Rustamzadeh, E., Hall, W. A., Todhunter, D. A., Vallera, V. D., Low, W. C., Liu, H., Panoskaltsis-Mortari, A. & Vallera, D. A., Jan 15 2007, In: International Journal of Cancer. 120, 2, p. 411-419 9 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
2006
Immunotoxin pharmacokinetics: A comparison of the anti-glioblastoma bi-specific fusion protein (DTAT13) to DTAT and DTIL13
Rustamzadeh, E., Vallera, D. A., Todhunter, D. A., Low, W. C., Panoskaltsis-Mortari, A. & Hall, W. A., May 2006, In: Journal of neuro-oncology. 77, 3, p. 257-266 10 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Intracranial therapy of glioblastoma with the fusion protein DTIL13 in immunodeficient mice
Rustamzadeh, E., Hall, W. A., Todhunter, D. A., Low, W. C., Liu, H., Panoskaltsis-Mortari, A. & Vallera, D. A., May 15 2006, In: International Journal of Cancer. 118, 10, p. 2594-2601 8 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2005
A bispecific recombinant immunotoxin, DT2219, targeting human CD19 and CD22 receptors in a mouse xenograft model of B-cell leukemia/lymphoma
Vallera, D. A., Todhunter, D. A., Kuroki, D. W., Shu, Y., Sicheneder, A. & Chen, H., May 15 2005, In: Clinical Cancer Research. 11, 10, p. 3879-3888 10 p.Research output: Contribution to journal › Article › peer-review
Open Access88 Scopus citations -
Molecular modification of a recombinant, bivalent anti-human CD3 immunotoxin (Bic3) results in reduced in vivo toxicity in mice
Vallera, D. A., Todhunter, D., Kuroki, D. W., Shu, Y., Sicheneder, A., Panoskaltsis-Mortari, A., Vallera, V. D. & Chen, H., Mar 2005, In: Leukemia research. 29, 3, p. 331-341 11 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
2004
A bispecific immunotoxin (DTAT13) targeting human IL-13 receptor (IL-13R) and urokinase-type plasminogen activator receptor (uPAR) in a mouse xenograft model
Todhunter, D. A., Hall, W. A., Rustamzadeh, E., Shu, Y., Doumbia, S. O. & Vallera, D. A., Feb 2004, In: Protein Engineering, Design and Selection. 17, 2, p. 157-164 8 p.Research output: Contribution to journal › Article › peer-review
63 Scopus citations -
2002
Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice
Li, C., Hall, W. A., Jin, N., Todhunter, D. A., Panoskaltsis-Mortari, A. & Vallera, D. A., 2002, In: Protein Engineering. 15, 5, p. 419-427 9 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations