Research output per year
Research output per year
Personal profile
Research interests
My research interest is focused on the discovery, the elucidation of the mode of action of natural and natural-based products as well as their promotion as high added-value bioactive compounds, mainly as therapeutic and anticancer agents.
I obtained my BSc and MSc at the University of Strasbourg (Strasbourg, France) and completed my PhD at the Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (Luxembourg, Grand Duchy of Luxembourg) in the framework of the European RedCat Project. As Marie Curie Fellow, my research project focused on the discovery and the elucidation of the mode of action of several natural and natural-based products as anticancer drugs. After acquisition of new skills in natural products isolation and structure elucidation at the Fundacíon MEDINA (Granada, Spain),
I joined the Schmidt-Dannert lab in October 2016 as Postdoctoral Research Associate. My research project aims to screen and isolate new antifungal compounds from Basidiomycota.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Universite de Lorraine
Sep 1 2009 → Dec 20 2013
Award Date: Dec 20 2013
Masters, Universite de Strasbourg
Sep 1 2007 → Jun 30 2009
Award Date: Jun 30 2009
Bachelors, Biochemistry and Molecular Biology, Universite Louis Pasteur
Sep 1 2004 → Jun 30 2007
Award Date: Jun 30 2007
External Positions
Chemist in Natural Products Chemistry, Fundación MEDINA
Nov 3 2014 → Jan 29 2015
PhD Student, Recherches Scientifiques Luxembourg asbl
Sep 1 2009 → Dec 20 2013
Research interests
- Natural Products
- Drug Discovery
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Molecular Identification and Antimicrobial Activity of Foliar Endophytic Fungi on the Brazilian Pepper Tree (Schinus terebinthifolius) Reveal New Species of Diaporthe
dos Santos, G. D., Gomes, R. R., Gonçalves, R., Fornari, G., Maia, B. H. L. N. S., Schmidt-Dannert, C., Gaascht, F., Glienke, C., Schneider, G. X., Colombo, I. R., Degenhardt-Goldbach, J., Pietsch, J. L. M., Costa-Ribeiro, M. C. V. & Vicente, V. A., Aug 2021, In: Current Microbiology. 78, 8, p. 3218-3229 12 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Discovery of antifungal and biofilm preventative compounds from mycelial cultures of a unique North American Hericium sp. Fungus
Song, X., Gaascht, F., Schmidt-Dannert, C. & Salomon, C. E., Feb 20 2020, In: Molecules. 25, 4, 963.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Coffee provides a natural multitarget pharmacopeia against the hallmarks of cancer
Gaascht, F., Dicato, M. & Diederich, M., Nov 1 2015, In: Genes and Nutrition. p. 1-17 17 p.Research output: Contribution to journal › Review article › peer-review
60 Scopus citations -
Novel inhibitors of human histone deacetylases: Design, synthesis and bioactivity of 3-alkenoylcoumarines
Seidel, C., Schnekenburger, M., Zwergel, C., Gaascht, F., Mai, A., Dicato, M., Kirsch, G., Valente, S. & Diederich, M., Aug 15 2014, In: Bioorganic and Medicinal Chemistry Letters. 24, 16, p. 3797-3801 5 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Plumbagin modulates leukemia cell redox status
Gaascht, F., Teiten, M. H., Cerella, C., Dicato, M., Bagrel, D. & Diederich, M., 2014, In: Molecules. 19, 7, p. 10011-10032 22 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations
Press/Media
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Mushrooms: The Pharmaceuticals of the Future
4/3/17
1 item of Media coverage
Press/Media: Expert Comment
Fellowships, Honors, and Prizes
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European Doctorate
Gaascht, Francois J (Recipient), Dec 20 2013
Prize: Prize (including medals and awards)