Harry T Orr

Professor, Laboratory Medicine and Pathology

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Expertise related to UN SDGs

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

Fingerprint

Dive into the research topics where Harry T Orr is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

10 Similar Profiles

Network

Recent external collaboration on country level. Dive into details by clicking on the dots.

6 Active
19 Finished

Etiology of cognitive decline in Spinocerebellar ataxia type 1
Cvetanovic, M., Araque, A. & Orr, H. T.
NIH NAT INST OF NEURO DISORDERS & STROKE
9/15/20 → 6/30/25
Project: Research project
Label-free Optical Imaging of Atrophy in SCA1 Mouse Models
Akkin, T. & Orr, H. T.
National Ataxia Foundation, Inc.
3/1/20 → 7/1/21
Project: Research project
Intraperitoneal (i.p.) injection of CCK receptor agonists
Orr, H. T.
CYDAN DEVELOPMENT, INC.
10/1/19 → 4/1/21
Project: Research project
Identifying symptomatic and neuroprotective strategies for cerebellar ataxia
Orr, H. T.
University of Michigan
4/15/19 → 3/31/24
Project: Research project
Cell signaling and neurodegeneration
Orr, H. T. & Walters, M. A.
NIH NAT INST OF NEURO DISORDERS & STROKE
5/1/18 → 4/30/23
Project: Research project

201 Article
31 Review article
9 Short survey
7 Chapter
More

Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1
Chopra, R., Bushart, D. D., Cooper, J. P., Yellajoshyula, D., Morrison, L. M., Huang, H., Scoles, D. R., Pulst, S. M., Orr, H. T. & Shakkottai, V. G., May 22 2020, In: Unknown Journal.
Research output: Contribution to journal › Article › peer-review
Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1
Chopra, R., Bushart, D. D., Cooper, J. P., Yellajoshyula, D., Morrison, L. M., Huang, H., Handler, H. P., Man, L. J., Dansithong, W., Scoles, D. R., Pulst, S. M., Orr, H. T. & Shakkottai, V. G., Oct 1 2020, In: Human molecular genetics. 29, 19, p. 3249-3265 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment
O'Callaghan, B., Hofstra, B., Handler, H. P., Kordasiewicz, H. B., Cole, T., Duvick, L., Friedrich, J., Rainwater, O., Yang, P., Benneyworth, M., Nichols-Meade, T., Heal, W., Ter Haar, R., Henzler, C. & Orr, H. T., Sep 4 2020, In: Molecular Therapy - Nucleic Acids. 21, p. 1006-1016 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1
Pinto, R. M., Arning, L., Giordano, J. V., Razghandi, P., Andrew, M. A., Gillis, T., Correia, K., Mysore, J. S., Grote Urtubey, D. M., Parwez, C. R., von Hein, S. M., Brent Clark, H., Nguyen, H. P., Förster, E., Beller, A., Jayadaev, S., Dirk Keene, C., Bird, T. D., Lucente, D., Vonsattel, J. P. & 4 others, Orr, H., Saft, C., Petrasch-Parwez, E. & Wheeler, V. C., Aug 1 2020, In: Human molecular genetics. 29, 15, p. 2551-2567 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations
Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism
Chao, O. Y., Marron Fernandez de Velasco, E., Pathak, S. S., Maitra, S., Zhang, H., Duvick, L., Wickman, K., Orr, H. T., Hirai, H. & Yang, Y. M., Jun 1 2020, In: Neuropsychopharmacology. 45, 7, p. 1159-1170 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations