Projects per year
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Collaborations and top research areas from the last five years
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Bi-substrate Inhibitors of SARS-CoV-2 Nsp14 Methyltransferase
Chen, L., Geraghty, R. J. & Xie, J.
NIH Nat'l Inst of Allergy & Infect Dis
6/15/22 → 5/31/24
Project: Research project
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Bi-substrate Inhibitors of SARS-CoV-2 Nsp14 Methyltransferase
National Institute of Allergy and Infectious Diseases
6/15/22 → 5/31/24
Project: Research project
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Optimizing Zika NS5 Methyltransferase Inhibitors
Chen, L., Geraghty, R. J. & Xie, J.
NIH Nat'l Inst of Allergy & Infect Dis
2/1/20 → 1/31/23
Project: Research project
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Optimizing Zika NS5 Methyltransferase Inhibitors
National Institute of Allergy and Infectious Diseases
2/1/20 → 1/31/22
Project: Research project
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Exploiting SIRT2 for Breast Cancer Therapy
EMORY UNIVERSITY, U.S. DEPARTMENT OF DEFENSE
8/1/19 → 7/31/21
Project: Research project
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5-((3-Amidobenzyl)oxy)nicotinamides as SIRT2 Inhibitors: A Study of Constrained Analogs
Ai, T., Wilson, D. & Chen, L., Nov 2023, In: Molecules. 28, 22, 7655.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation
Zhang, Q., Tang, W., Stancanelli, E., Jung, E., Syed, Z., Pagadala, V., Saidi, L., Chen, C. Z., Gao, P., Xu, M., Pavlinov, I., Li, B., Huang, W., Chen, L., Liu, J., Xie, H., Zheng, W. & Ye, Y., Dec 2023, In: Nature communications. 14, 1, 5777.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Bisubstrate Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 Nsp14 Methyltransferase
Jung, E., Soto-Acosta, R., Xie, J., Wilson, D. J., Dreis, C. D., Majima, R., Edwards, T. C., Geraghty, R. J. & Chen, L., Sep 8 2022, In: ACS Medicinal Chemistry Letters. 13, 9, p. 1477-1484 8 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Zika Virus Inhibitors Based on a 1,3-Disubstituted 1H-Pyrazolo[3,4-d]pyrimidine-amine Scaffold
Jung, E., Soto-Acosta, R., Geraghty, R. J. & Chen, L., Sep 2022, In: Molecules. 27, 18, 6109.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
4,7-disubstituted 7h-pyrrolo[2,3-d]pyrimidines and their analogs as antiviral agents against zika virus
Soto-Acosta, R., Jung, E., Qiu, L., Wilson, D. J., Geraghty, R. J. & Chen, L., Jul 1 2021, In: Molecules. 26, 13, 3779.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations