Medical errors are a major concern in clinical practice, suggesting the need for advanced surgical aids for preoperative planning and rehearsal. Conventionally, CT and MRI scans, as well as 3D visualization techniques, have been utilized as the primary tools for surgical planning. While effective, it would be useful if additional aids could be developed and utilized in particularly complex procedures involving unusual anatomical abnormalities that could benefit from tangible objects providing spatial sense, anatomical accuracy, and tactile feedback. Recent advancements in 3D printing technologies have facilitated the creation of patient-specific organ models with the purpose of providing an effective solution for preoperative planning, rehearsal, and spatiotemporal mapping. Here, we review the state-of-the-art in 3D printed, patient-specific organ models with an emphasis on 3D printing material systems, integrated functionalities, and their corresponding surgical applications and implications. Prior limitations, current progress, and future perspectives in this important area are also broadly discussed.
|Original language||English (US)|
|Number of pages||20|
|Journal||Annual Review of Analytical Chemistry|
|State||Published - Jun 12 2018|
Bibliographical noteFunding Information:
The authors acknowledge support from the MnDRIVE RSAM Initiative and the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health (NIH) (award 1DP2EB020537). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. G.H. acknowledges support from the graduate school of the University of Minnesota (UMN 2017-18 Interdisciplinary Doctoral Fellowship). The authors thank Dr. Guru Venkatesan and Dr. Nathan Carter for their valuable comments and suggestions during manuscript preparation.
© Copyright 2018 by Annual Reviews. All rights reserved.
- 3D printing
- integrated functionalities
- organ models
- polymeric materials
- surgical applications
- tissue-mimicking materials
PubMed: MeSH publication types
- Journal Article
- Research Support, Non-U.S. Gov't
- Research Support, N.I.H., Extramural