A mercaptoacetamide-based Class II histone deacetylase inhibitor increases dendritic spine density via RasGRF1/ERK pathway

Medicine & Life Sciences

• Dendritic Spines 100%
• Histone Deacetylase Inhibitors 96%
• MAP Kinase Signaling System 90%
• ras-GRF1 20%
• Neurons 14%
• Messenger RNA 13%
• Amyloid 11%
• Synapses 10%
• Transfection 10%
• Cognitive Dysfunction 9%
• Psychological Inhibition 9%
• Real-Time Polymerase Chain Reaction 9%
• Alzheimer Disease 9%
• Spine 9%
• Proteins 8%
• Learning 8%
• Memory 8%
• Immunohistochemistry 8%
• Staining and Labeling 7%
• Growth 5%
• In Vitro Techniques 5%

Social Sciences

• cognitive impairment 33%
• dementia 27%
• cause 16%
• performance 12%
• time 9%
• learning 9%