A simple and precise method of determining true sodium, potassium, and chloride concentrations in hyperlipemia

Michael W Steffes, Esther F. Freier

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

Sodium, potassium, and chloride levels are artifactually depressed in hyperlipemic sera. Accurate electrolyte levels are needed for management of patients with hyperlipemia, but present methods for correcting the values (serum water and/or osmolality determinations) either are technically cumbersome or fail to provide accurate data to correct the falsely low levels. Alternatively, to determine true sodium, potassium, and chloride concentrations in hyperlipemic sera, only the required electrolyte values and the triglycerides are measured. The percentage by which the measured electrolyte levels in the hyperlipemic sample must be increased to approximate the true values is given by the following equation: per cent increase = 2.1 × triglycerides (Gm./dl.) -0.6.

Original languageEnglish (US)
Pages (from-to)683-688
Number of pages6
JournalThe Journal of Laboratory and Clinical Medicine
Volume88
Issue number4
StatePublished - Oct 1976

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