A symbolic environment for visualizing activated foci in functional neuroimaging datasets

Kelly Rehm, Kamakshi Lakshminaryan, Sally Frutiger, Kirt A. Schaper, Witt De Sumners, Stephen C. Strother, Jon R. Anderson, David A. Rottenberg

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


This paper presents a symbolic visualization environment known as the Corner Cube environment, which was developed to facilitate rapid examination and comparison of activated foci defined by analyses of functional neuroimaging datasets. We have performed a comparative evaluation of this environment against maximum-intensity projection and 'gallery of slices' displays, and the results suggest that the Corner Cube environment has definite advantages over both conventional display techniques. We conclude that the Corner Cube is an effective tool for summarizing the spatial characteristics of activated foci within an easily understood visual context and is especially useful for displaying the similarities and differences in functional neuroimaging datasets.

Original languageEnglish (US)
Pages (from-to)215-226
Number of pages12
JournalMedical Image Analysis
Issue number3
StatePublished - Jan 1 1998

Bibliographical note

Funding Information:
This work has been financially supported by the US Department of Veterans Affairs and by National Institutes of Health grants DA09246, NS33718, NS25701 and MH57180. Dr Rehm received support from research training grant T15LM07041 from the National Institutes of Health.


  • Brain mapping
  • Computer graphics
  • Computer-assisted image processing
  • Emission-computed tomography
  • Observer performance experiment
  • Statistical models

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