Antihistamines block radiation-induced taste aversions

Carolyn J. Levy; Marilyn E. Carroll; James C. Smith; Kurt G. Hofer

doi:10.1126/science.186.4168.1044

Antihistamines block radiation-induced taste aversions

Carolyn J. Levy, Marilyn E. Carroll, James C. Smith, Kurt G. Hofer

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions.

Original language	English (US)
Pages (from-to)	1044-1045
Number of pages	2
Journal	Science
Volume	186
Issue number	4168
DOIs	https://doi.org/10.1126/science.186.4168.1044
State	Published - 1974
Externally published	Yes

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title = "Antihistamines block radiation-induced taste aversions",

abstract = "When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions.",

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Antihistamines block radiation-induced taste aversions

Abstract

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