Antihistamines block radiation-induced taste aversions

Carolyn J. Levy, Marilyn E. Carroll, James C. Smith, Kurt G. Hofer

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions.

Original languageEnglish (US)
Pages (from-to)1044-1045
Number of pages2
Issue number4168
StatePublished - 1974
Externally publishedYes


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