Autonomous immunity in mucosal epithelial cells: fortifying the barrier against infection

Karen F. Ross; Mark C. Herzberg

doi:10.1016/j.micinf.2016.03.008

Autonomous immunity in mucosal epithelial cells: fortifying the barrier against infection

Karen F. Ross, Mark C. Herzberg

Basic Sciences

Research output: Contribution to journal › Short survey › peer-review

18 Scopus citations

Abstract

Mucosal epithelial cells express an autonomous innate immune response that controls the overgrowth of invaded bacteria, mitigates the harmful effects of the bacteria carried within, and does not rely on other external arms of the immune response. Epithelial cell autonomous innate immunity “respects” the social biology of invading bacteria to achieve symbiosis, and is the primary protective mechanism against pathogens.

Original language	English (US)
Pages (from-to)	387-398
Number of pages	12
Journal	Microbes and Infection
Volume	18
Issue number	6
DOIs	https://doi.org/10.1016/j.micinf.2016.03.008
State	Published - Jun 1 2016

Bibliographical note

Publisher Copyright:
© 2016

Keywords

Antimicrobial proteins
Cell signaling
Infection
Innate immunity
Mucosal epithelium

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10.1016/j.micinf.2016.03.008

http://europepmc.org/articles/pmc4884473

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abstract = "Mucosal epithelial cells express an autonomous innate immune response that controls the overgrowth of invaded bacteria, mitigates the harmful effects of the bacteria carried within, and does not rely on other external arms of the immune response. Epithelial cell autonomous innate immunity “respects” the social biology of invading bacteria to achieve symbiosis, and is the primary protective mechanism against pathogens.",

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AU - Herzberg, Mark C.

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KW - Cell signaling

KW - Infection

KW - Innate immunity

KW - Mucosal epithelium

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Autonomous immunity in mucosal epithelial cells: fortifying the barrier against infection

Abstract

Bibliographical note

Keywords

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