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Aziridinyl quinone antitumor agents based on indoles and cyclopent[b]indoles: Structure-activity relationships for cytotoxicity and antitumor activity
E. B. Skibo, C. Xing, R. T. Dorr
Research output
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Contribution to journal
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Article
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peer-review
91
Scopus citations
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Dive into the research topics of 'Aziridinyl quinone antitumor agents based on indoles and cyclopent[b]indoles: Structure-activity relationships for cytotoxicity and antitumor activity'. Together they form a unique fingerprint.
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Medicine & Life Sciences
cyclodrine
100%
Indoles
78%
NAD(P)H Dehydrogenase (Quinone)
71%
quinone
58%
Structure-Activity Relationship
57%
Antineoplastic Agents
46%
Substrate Specificity
31%
Alkylation
27%
indole
27%
Quinones
20%
Alkylating Agents
16%
Cytostatic Agents
15%
DNA
15%
apaziquone
13%
Quantitative Structure-Activity Relationship
9%
Respect
7%
Non-Small Cell Lung Carcinoma
6%
Poisons
5%
Neoplasms
4%
Cell Line
4%
Chemical Compounds
Indoles
50%
Quinone
46%
Antitumor
45%
Antineoplastic Agent
43%
Structure-Activity Relationship
41%
Indole
34%
Alkylating Agent
28%
Reductive Alkylation
16%
Lethal
14%
Vmax
13%
QSAR Study
12%
Alkylation
10%
Toxic
9%