Catechol-O-Methyltransferase val158met Polymorphism Predicts Placebo Effect in Irritable Bowel Syndrome

Agriculture & Biology

• irritable bowel syndrome 91%
• catechol O-methyltransferase 80%
• placebos 58%
• genetic polymorphism 39%
• health care workers 6%
• homozygosity 5%
• pain 5%
• dopamine 5%
• signs and symptoms (animals and humans) 4%
• learning 4%
• biomarkers 4%
• methionine 4%
• alleles 3%
• metabolism 3%
• enzymes 2%

Medicine & Life Sciences

• Catechol O-Methyltransferase 73%
• Placebo Effect 66%
• Irritable Bowel Syndrome 60%
• Placebos 36%
• Homozygote 7%
• Methionine 6%
• Therapeutics 6%
• Reward 6%
• Health Personnel 5%
• Dopamine 5%
• Patient Care 5%
• Learning 4%
• Alleles 4%
• Memory 4%
• Randomized Controlled Trials 4%
• Health Care Outcome Assessment 4%
• Clinical Trials 4%
• Biomarkers 4%
• Pain 3%
• Enzymes 3%

Chemical Compounds

• Met-Met 100%
• Methionine 27%
• Dopamine 25%
• Biological Marker 24%