Cellular signalling: STIMulating calcium entry

Jonathan S. Marchant

doi:10.1016/j.cub.2005.06.035

Cellular signalling: STIMulating calcium entry

Jonathan S. Marchant

Research output: Contribution to journal › Short survey › peer-review

16 Scopus citations

Abstract

The molecular identity of the signal coupling intracellular Ca²⁺ store depletion to the activation of Ca²⁺ entry has long resisted exposure. Two recent studies independently implicate the STIM protein family as essential components in this coupling. These data provide new impetus to resolve how store Ca²⁺ content is sensed and communicated to store-operated Ca²⁺ channels at the cell surface.

Original language	English (US)
Pages (from-to)	R493-R495
Journal	Current Biology
Volume	15
Issue number	13
DOIs	https://doi.org/10.1016/j.cub.2005.06.035
State	Published - Jul 12 2005
Externally published	Yes

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title = "Cellular signalling: STIMulating calcium entry",

abstract = "The molecular identity of the signal coupling intracellular Ca2+ store depletion to the activation of Ca2+ entry has long resisted exposure. Two recent studies independently implicate the STIM protein family as essential components in this coupling. These data provide new impetus to resolve how store Ca2+ content is sensed and communicated to store-operated Ca2+ channels at the cell surface.",

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AB - The molecular identity of the signal coupling intracellular Ca2+ store depletion to the activation of Ca2+ entry has long resisted exposure. Two recent studies independently implicate the STIM protein family as essential components in this coupling. These data provide new impetus to resolve how store Ca2+ content is sensed and communicated to store-operated Ca2+ channels at the cell surface.

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Cellular signalling: STIMulating calcium entry

Abstract

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