TY - JOUR
T1 - Cholesterol, lipoproteins, high-sensitivity c-reactive protein, and other risk factors for atherosclerosis
AU - Rudolf, Joseph
AU - Lewandrowski, Kent B.
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014/3
Y1 - 2014/3
N2 - Coronary heart disease is a common and costly epidemic in the Western world. Intensive study has led to a deeper understanding of the pathogenesis of coronary disease and risk stratification. Traditional risk factor assessment has focused on parameters derived from the Framingham Heart Study (age, hypertension, cholesterol, family history, and cigarette smoking). New emerging risk factors, both biological and genetic, are reshaping the understanding of heart disease and the approach to risk stratification. As these emerging assays become more standardized, automated, and inexpensive to perform, they are becoming increasingly important tools in the assessment and treatment of coronary heart disease.
AB - Coronary heart disease is a common and costly epidemic in the Western world. Intensive study has led to a deeper understanding of the pathogenesis of coronary disease and risk stratification. Traditional risk factor assessment has focused on parameters derived from the Framingham Heart Study (age, hypertension, cholesterol, family history, and cigarette smoking). New emerging risk factors, both biological and genetic, are reshaping the understanding of heart disease and the approach to risk stratification. As these emerging assays become more standardized, automated, and inexpensive to perform, they are becoming increasingly important tools in the assessment and treatment of coronary heart disease.
KW - Apolipoprotein E
KW - Atherosclerosis
KW - Biomarkers
KW - Cardiac markers
KW - Cholesterol biomarker
KW - High-sensitivity CRP
KW - Laboratory medicine
KW - Lipoprotein
UR - http://www.scopus.com/inward/record.url?scp=84895100162&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84895100162&partnerID=8YFLogxK
U2 - 10.1016/j.cll.2013.11.003
DO - 10.1016/j.cll.2013.11.003
M3 - Review article
C2 - 24507791
AN - SCOPUS:84895100162
SN - 0272-2712
VL - 34
SP - 113
EP - 127
JO - Clinics in Laboratory Medicine
JF - Clinics in Laboratory Medicine
IS - 1
ER -