TY - JOUR
T1 - Clinical utility of the IRF
T2 - assessment of erythroid regeneration following parvo B19 infection.
AU - Wyrick-Glatzel, Janis
AU - Conway-Klaassen, Janice
PY - 2002/9/1
Y1 - 2002/9/1
N2 - Parvo B19 (Fifth disease) is an erythrotropic virus which attaches through the 'P' globoside receptor on the surface of human red blood cells and precursors. This typically benign viral infection can cause a transient aplastic anemia in patients with underlying red cell disorders. In this case, a two-year-old child presents with severe aplastic anemia without evidence of underlying disease. Erythroid regeneration is monitored through the use of the immature reticulocyte fraction (IRF) and is demonstrated by the presence of high and medium fluorescence reticulocytes in the peripheral blood three to five days prior to the peak in absolute reticulocytes.
AB - Parvo B19 (Fifth disease) is an erythrotropic virus which attaches through the 'P' globoside receptor on the surface of human red blood cells and precursors. This typically benign viral infection can cause a transient aplastic anemia in patients with underlying red cell disorders. In this case, a two-year-old child presents with severe aplastic anemia without evidence of underlying disease. Erythroid regeneration is monitored through the use of the immature reticulocyte fraction (IRF) and is demonstrated by the presence of high and medium fluorescence reticulocytes in the peripheral blood three to five days prior to the peak in absolute reticulocytes.
UR - http://www.scopus.com/inward/record.url?scp=0037704308&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037704308&partnerID=8YFLogxK
M3 - Article
C2 - 12776780
AN - SCOPUS:0037704308
SN - 0894-959X
VL - 15
SP - 208
EP - 212
JO - Clinical laboratory science : journal of the American Society for Medical Technology
JF - Clinical laboratory science : journal of the American Society for Medical Technology
IS - 4
ER -