Conformationally restrained carbazolone-containing α,γ-diketo acids as inhibitors of HIV integrase

Medicine & Life Sciences

• HIV Integrase Inhibitors 100%
• Acids 45%
• Integrases 29%
• Nitrogen 14%
• Integrase Inhibitors 11%
• Halogens 10%
• Alkylation 9%
• Structure-Activity Relationship 8%
• Highly Active Antiretroviral Therapy 8%
• Catalytic Domain 6%
• Electrons 5%

Chemical Compounds

• Acid 20%
• Integrase Inhibitor 11%
• Antiretroviral 10%
• Modification 8%
• Halogen 6%
• Structure-Activity Relationship 6%
• Alkylation 6%
• Nitrogen Atom 6%
• Nitrogen 4%