TY - JOUR
T1 - Cortical areas activated by bilateral galvanic vestibular stimulation
AU - Lobel, Elie
AU - Kleine, Justus F.
AU - Leroy-Willig, Anne
AU - Van De Moortele, Pierre François
AU - Le Bihan, Denis
AU - Grüsser, Otto Joachim
AU - Berthoz, Alain
PY - 1999
Y1 - 1999
N2 - The brain areas activated by bilateral galvanic vestibular stimulation (GVS) were studied using functional magnetic resonance imaging. In six human volunteers, GVS led to activation in the region of the temporoparietal junction, the central sulcus, and the anterior interior intraparietal sulcus, which may correspond to macaque areas PIVC, 3aV, and 2v, respectively. In addition, activation was found in premotor regions of the frontal lobe, presumably analogous to areas 6pa and 8a in the monkey. Since these areas were not detected in previous studies using caloric vestibular stimulation, they could be related to the modulation of otolith afferent activity by GVS. However, the simple paradigm used did not allow separation of the otolithic and semicircular canal effects of GVS. Further studies must be performed to clarify the question of cortical representation of the otolithic information in the human and monkey brain.
AB - The brain areas activated by bilateral galvanic vestibular stimulation (GVS) were studied using functional magnetic resonance imaging. In six human volunteers, GVS led to activation in the region of the temporoparietal junction, the central sulcus, and the anterior interior intraparietal sulcus, which may correspond to macaque areas PIVC, 3aV, and 2v, respectively. In addition, activation was found in premotor regions of the frontal lobe, presumably analogous to areas 6pa and 8a in the monkey. Since these areas were not detected in previous studies using caloric vestibular stimulation, they could be related to the modulation of otolith afferent activity by GVS. However, the simple paradigm used did not allow separation of the otolithic and semicircular canal effects of GVS. Further studies must be performed to clarify the question of cortical representation of the otolithic information in the human and monkey brain.
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U2 - 10.1111/j.1749-6632.1999.tb09194.x
DO - 10.1111/j.1749-6632.1999.tb09194.x
M3 - Article
C2 - 10372081
AN - SCOPUS:0343284767
SN - 0077-8923
VL - 871
SP - 313
EP - 323
JO - Annals of the New York Academy of Sciences
JF - Annals of the New York Academy of Sciences
ER -